The COVID-10 pandemic has a significant impact on economic conditions in Indonesia. It can be seen by the continued decline in the Jakarta composite index which has reached 21% in 2020 resulting in health and economic crises. Many businesses have shut down, and the decline in stock returns is one of the negative effects felt by PT. Mitra Keluarga Karya Sehat. Tbk. MIKA's share price hit its lowest level at second quarter of 2019 , with the lowest price ever reaching 1.895 on that year. This study aims to analyse the financial performance of MIKA, a hospital company listed on the Indonesia stock exchange (IDX), and to identify factors that affect stock return, financial data from 2013 to the COVID-19 pandemic data in 2022 and considers factors such as profitability, leverage, liquidity ratio, TATO, market return, stock return, and COVID-19 period. The research utilizes quantitative research methods and purposive sampling, analyzing audited quarterly financial reports from 2013 to 2022. In this study, OLS is used as a reference for the spatial regression model. In this research, profitability has a positive and significant effect on stock returns. This means investing in different types of assets or sectors to reduce the risk associated with market movements. If the company has an investment strategy, consider changing or adapting the strategy to better align with research findings. In business, adapting and responding to strong research findings is key to remaining competitive and successful in the marketplace.